Radiesse vs. Sculptra: Which is Right for You?

Dermal fillers are a popular non-surgical solution for facial rejuvenation, non-surgical butt lifts, and treating pesky wrinkles on the hands and neck. Whether you want a more defined jawline or want to smooth out wrinkles and fine lines. A few quick injections can provide you with impressive, natural-looking results. Two of the most popular dermal fillers include Radiesse and Sculptra. Both have a completely different composition and require different injection techniques. If you’re interested in receiving dermal fillers to help you maintain your youthful appearance but aren’t sure which is right for you, we’re here to help. In this article, we’ll explore the key differences and similarities between Sculptra and Radiesse so you can decide which is best for your personal aesthetic goals.

Here’s everything you need to know about Sculptra vs. Radiesse:

Similarities Between The Two Treatments

Sculptra and Radiesse are different types of dermal fillers that differ from the popular HA fillers. While there are many differences in longevity and composition, they both provide similar results. Both Sculptra and Radiesse are used to reduce the appearance of wrinkles, fine lines, and folds. They can also help combat volume loss in the face and stimulate collagen production. Both formulas also contain biocompatible ingredients that are well tolerated by the body. While there’s always a risk of side effects like redness, bruising, and swelling with dermal fillers, both are well-tested and clinically proven to deliver results.

The Key Differences Between Sculptra and Radiesse

There are many advantages to both of these types of dermal fillers. However, to ensure you find the best dermal fillers for your aesthetic goals, it’s best to weigh the pros and cons of the key differences.

Here’s how Sculptra vs. Radiesse compare.

Composition And Ingredients

Most dermal fillers contain the active ingredient Hyaluronic acid. This is an ingredient that is naturally occurring in the body. However, both Sculptra and Radiesse are different than typical HA fillers. The main ingredients in Sculptra are poly-L-lactic acid, carboxymethylcellulose, and non-pyrogenic mannitol. There is also sterile water in the composition to help with the injection. Sculptra is a gel-like substance expertly formulated with ingredients that help stimulate collagen production. While the main ingredients in Radiesse are synthetic calcium hydroxylapatite microspheres. Synthetic calcium hydroxylapatite is a biocompatible material that helps your body produce collagen and add volume. Radiesse can also be used to improve skin tone and texture.

Targeted Areas

When deciding between the two different types of dermal filler, it’s best to consider your unique aesthetic goals and what concerns you want to target with the treatment.  Radiesse is designed to fill deep wrinkles, skin folds, smile lines, and marionette lines. This dermal filler is ideal for treating deep wrinkles on the lower part of the face. With a few syringes of Radiesse, patients can achieve a more youthful complexion and a more overall lifted appearance. Radiesse lip fillers and Radiesse neck treatments are popular volume restorative treatments. While Sculptra is great for restoring volume around the cheeks and temples. It’s an ideal choice for individuals struggling with hallowing and loss of volume caused by aging. Sculptra is commonly used for facial contouring and can help you achieve a more refined appearance. Depending on the imperfections you want to fix with dermal fillers, many individuals pair Sculptra and Radiesse together to achieve a more youthful appearance. Sculptra and Radiesse are also commonly used for the neck, buttocks, hands, and lips. A Sculptra butt lift can provide a gradual volume enhancement. While a Radiesse butt lift can deliver immediate results for volume enhancements.

Results Timeline

The results timeline is one of the main differences between Radiesse vs. Sculptra. After Sculptra injections, your skin will react to the injection by producing more collagen. This means it may take several weeks to see results. While patients notice immediate results after Radiesse injections. However, the timeline of results will depend on the injection site. For example, a Radiesse butt lift may provide immediate results, but you may notice slight enhancements over time. Radiesse lip fillers will likely provide immediate results after the treatment.


Even though it takes longer to see results with Sculptra, the results from the treatment can last around 18-24 months. While the results from Radiesse last approximately one year. Patients can receive maintenance treatments to prolong the longevity of their results from either Sculptra or Radiesse. Many patients choose to start with Sculptra and then get Radiesse maintenance treatments.

Potential Side Effects And Risks

It’s important to note that bruising, redness, swelling, and itchiness are common side effects for most dermal fillers. Both treatments are safe and clinically tested. Most side effects don’t last longer than seven days. Patients who choose Sculpta may experience the common side effects of dermal fillers. Some patients have also experienced a change in skin tone. These symptoms reside relatively quickly. The calcium microspheres in the Radiesse formula can cause swelling, redness, and itching around the injection site. In rare occurrences, patients may also develop lumps or nodules.

Cost Comparison

Radiesse is typically more affordable than Sculptra. The cost for one syringe of Radiesse is around XXXX, while Sculptra cost is around XXXX.  The number of sessions and syringes you receive will dictate the overall cost of the treatment. The price can also vary depending on who you go to for treatment.The cost will also vary depending on the treatment location. A Sculptra bull lift will inevitably cost more than Radiesse lip fillers since they require more syringes and treatments.

Choosing The Right Treatment For You with Egozi

When comparing Sculptra vs. Radiesse, it really boils down to personal preference. Sculptra may be better if you’re struggling with hallowing or volume loss. If your concern is wrinkles, skin folds, and fine lines, Radiesse may be more suitable for your needs. Dermal fillers are a minimally invasive solution that can deliver long-lasting results. While comparing the pros and cons of both treatments, it’s always best to meet with a plastic surgeon or your medical provider to discuss the next steps.    Once you’ve scheduled a consultation with Dr. Eric Egozi, the Egozi Plastic Surgery team will help you decide between Sculptra vs. Radiesse and provide expert recommendations based on your goals and skin type.

Schedule a consultation today to get started. 

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